Bring a large pot of lightly salted water to boil. Pour in rigatoni and cook until al dente, about 8 to 10 minutes. Drain and set pasta aside.
Meanwhile brown beef and pork mince in a large frypan over medium heat. With a slotted spoon, remove mince to a baking dish. Stir mushrooms, spaghetti sauce and cooked pasta into the baking dish. Sprinkle cheese and pepperoni over the top.
Bake in preheated oven until the cheese is brown and bubbly, about 20 minutes.